SensiStainTM Anti-Recombinant PD-L1 Antibody is designed to detect Programmed Death-Ligand 1 (PD-L1), also known as CD274 or B7 Homolog 1 (B7-H1). PD-L1 is a transmembrane protein involved in suppressing the immune system making tumor cells resistant to CD8+ T cell-mediated lysis through binding of the Programmed Death-1 (PD-1) receptor. Studies have shown overexpression of PD-L1 may allow cancer cells to evade the actions of the host immune system.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
kappa, IgG1
Raised In
Mouse
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
PD-L1
Note
1:50-1:200
Clone No
IHC441
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.