SensiStainTM Anti-p21 Antibody detects for the presence or absence of p21 (also known as p21Cip1 , p21Waf1, cyclin-dependent kinase inhibitor 1, or CDK-interacting protein 1) which functions to regulate the cell cycle at G1 through cyclin-CDK2 or cyclin-CDK4 complex inhibition. Decrease expression in p21 is linked to poor prognosis in a number of carcinomas. Normally p21 is expressed in all healthy adult human tissues.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
IgG2a
Raised In
Mouse
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
p21
Note
1:50-1:200
Clone No
IHC021
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.