Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains - kappa and lambda. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. Antibodies against lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
IgG1
Raised In
Mouse
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
Lambda
Note
1:50-1:200
Clone No
IHC709
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.