SensiStainTM Anti-Collagen Type IV Antibody is designed for detection of collagen IV protein expressing tissue or lysates. Collagen IV is found in the basal lamina and a constituent of the basement membrane which has a role in supporting structure. Disruptions or complete absent of basement membrane may be indicative of upregulation of matrix metalloproteinases secreted by cancer cells. The loss of structure integrity of the basement membrane is associated with stages of invasive cancers.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Recombinant Protein
Immunogen Region
Recombinant Protein
Isotype
IgG1
Raised In
Mouse
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
Collagen Type IV
Note
1:50-1:200
Clone No
IHC549
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Applications
ELISA, IHC
Reviews of SensiStain™ Anti-Collagen Type IV Antibody