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Home / Primary Antibodies / IHC Antibodies

SensiStain™ Anti-BSEP Antibody

SKU : BHA10924691

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Applied Biological Materials (abm) Inc.

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Mfr.No.	HY000021
Categories	Primary Antibodies
Clonality	monoclonal
Description	SensiStainTM Anti-BSEP Antibody is validated for the detection of bile salt export pump (BSEP) which has a role in the transport of bile acid, taurocholate, and other cholate conjugates across the hepatocyte canalicular membrane. BSEP has been associated with disorders such as, progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2).Bile Salt Export Pump (BSEP) is a membrane associated protein encoded by the ABCB11 gene – a member of the superfamily ATP-binding cassette (ABC) transporters. BSEP functions as a canalicular bile salt export pump and facilitates the transport of bile acid and other cholate conjugates across the canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 is an inherited disorder linked to mutations in the BSEP gene that increase the risk of developing cholestatic liver disease and hepatocellular carcinoma early in life.
Formulation	Liquid
Host	Mouse(Mu)
Guarantee	abm guarantees that all our SensiStain™ Anti-BSEP Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen	Recombinant Human BSEP
Isotype	IgG1
Quantity	100 µg/ 100 µl
Recommended Dilution	1:1000-1:3000
Relevance	UniProtKB: O95342
Shipping Condition	Ice Packs
Species Reactivity	Human
Specificity	Human BSEP

Gene Name	ABCB11
Clone No	AHC0021

Concentration	100 µg/ 100 µl
Purity	Protein A/G Affinity Purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Storage Condition	-20C

Description	IHC

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SKU	Supplier No.	Size	Your price	Quantity
BHA10924691	HY000021	0.1 ml	$282.75		Add to Cart

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