SensiStainTM Anti-BRAF V600E Antibody detects the V600E mutant form of BRAF (serine/threonine-protein kinase B-Raf). Studies have shown that mutations on the BRAF gene in which 80% are of the single V600E substitution resulted in increase of cell proliferation and resistance to apoptosis. BRAF V600E is therefore an important immunohistochemical marker for tumor studies.
Formulation
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Immunogen
Synthetic BRAF V600E Peptide
Immunogen Region
Synthetic BRAF V600E Peptide
Isotype
IgG2b
Raised In
Mouse
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
BRAFV600E
Note
0.0625
Clone No
IHC600
Purity
Purified
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.