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Home / Antibodies

SAM68 Antibody / Src associated in mitosis 68 kDa protein (F53819)

SKU : BHA17102430

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Mfr.No.	F53819, F53819-0.05ML, F53819-0.2ML
Clonality	Polyclonal
Description	Src associated in mitosis 68 kDa protein is recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmic export of unspliced (CTE)-containing RNA species according to.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 259-291 from the human protein was used as the immunogen for the SAM68 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse
Reactivity	Human, Mouse
Recombinant	No
Subcellular Location	Nuclear

Uniprot	Q07666
Gene Id	10657

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the SAM68 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC-P
Dilution	Weste blot: 1:1000-2000,Immunohistochemistry (FFPE): 1:25

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102430-1	F53819-0.05ML	0.05ml	$165		Add to Cart
BHA17102430-2	F53819-0.2ML	0.2ml	$379		Add to Cart

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