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Home / Primary Antibodies / Monoclonal Antibodies

Recombinant CALD1 Antibody/ Caldesmon / CAD (HMW)

SKU : BHA17119786

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NSJ Bioreagents

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Mfr.No.	V9402, V9402-20UG, V9402-100UG
Clonality	Recombinant Mouse Monoclonal
Description	Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant human full-length CALD1 protein was used as the immunogen for the recombinant CALD1 antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human
Note	Optimal dilution of the recombinant CALD1 antibody should be determined by the researcher.

Uniprot	Q05682

Format	Purified
Purity	Protein A/G affinity
Storage	Aliquot the recombinant CALD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml

Product Manual	Datasheet

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