JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Home / Primary Antibodies / Polyclonal Antibodies

Rabbit Anti-Human HSP40 Polyclonal (SPC-100)

BHA11906205
Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
Request More Infos
Order Now

Credit card payments now incur a 3% fee.

Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
Ask Merchant
Request More Infos
Sample Request
Antigen HSP40
Swissprot P25685
Accession Number NP_006136.1
Gene Id 3337
Target HSP40
Research Area Cancer, Heat Shock, Cell Signaling, Chaperone Proteins, Protein Trafficking
Buffer Rabbit Antiserum
Concentration N/A
Dilutions WB (1:2000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Rabbit Antiserum
Scientific Background DnaJ/HSP40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, HSP70s. Because the ATP hydrolysis is essential for the activity of HSP70s, DnaJ/HSP40 proteins actually determine the activity of HSP70s by stabilizing their interaction with substrate proteins. DnaJ/HSP40 proteins all contain the J domain through which they bind to HSP70s.
HSP40, also known as HDJ1 (6), is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1 (2-5). HSP 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli; an intracellular pattern similar to HSC70/HSP70, the mammalian homologues of the bacterial heat shock protein, DnaK (2).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~40kDa.
Storage -20ºC
Storage Buffer Rabbit Antiserum *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IP, WB, ICC/IF
Description WB ; ICC ; IF ; IP
Dilution WB (1:2000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Melville, M. W. et al. (1997) PNAS USA, 94: 97-102.

2. Hattori, H., Liu, Y-C., Tohnai, I., Ueda, M., Kaneda, T., Kobayashi, T., Tanabe, K., and Ohtsuka, K. (1992) Cell Structure and Function 17: 77-86.

3. Ohtsuka, K. Masuda, A., Nakai, A., and Nagata, K. (1990) Biochem. Biophys. Res. Commun. 166: 642-647.

4. Bardwell, J.C.A., Tilly, K., Craig, E., King, J., Zylicz, M. and Georgopoulos, C. (1986) J. Biol. Chem. 261: 1782-1785.

5. Ohku, M., Tamura, F., Nishimura, S., and Uchida, H. (1986) J. Biol. Chem. 261: 1778-1781.

6. Ohtsuka, K. (1993) Biochem. Biophys. Res. Commun. 197: 235-240.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11906205-1 SPC-100D Unconjugated 100 ul $334
Add to Cart
BHA11906205-2 SPC-100D-A390 ATTO 390 100 ul $389
Add to Cart
BHA11906205-3 SPC-100D-A488 ATTO 488 100 ul $388
Add to Cart
BHA11906205-4 SPC-100D-A594 ATTO 594 100 ul $388
Add to Cart
BHA11906205-5 SPC-100D-APC APC 100 ul $386
Add to Cart
BHA11906205-6 SPC-100D-BI Biotin 100 ul $383
Add to Cart
BHA11906205-7 SPC-100D-FITC FITC 100 ul $378
Add to Cart
BHA11906205-8 SPC-100D-HRP HRP 100 ul $373
Add to Cart
BHA11906205-9 SPC-100D-PCP PerCP 100 ul $386
Add to Cart
BHA11906205-10 SPC-100D-RPE RPE 100 ul $384
Add to Cart
BHA11906205-11 SPC-100S Unconjugated 12 ul $45
Add to Cart