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Home / Antibodies

Protocadherin alpha-C2 Antibody / PCDHAC2 (F54638)

SKU : BHA17103104

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Mfr.No.	F54638, F54638-0.08ML, F54638-0.4ML
Clonality	Polyclonal
Description	This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alteative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 616-644 from the human protein was used as the immunogen for the Protocadherin alpha-C2 antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	Q9Y5I4

Format	Purified
Purification	Antigen affinity purified
Storage	Aliquot the Protocadherin alpha-C2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	FACS, IF, IHC-P, WB
Dilution	Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25, Immunohistochemistry (FFPE): 1:25, Weste blot: 1:500-1:2000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103104-1	F54638-0.08ML	0.08ml	$165		Add to Cart
BHA17103104-2	F54638-0.4ML	0.4ml	$379		Add to Cart

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