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Home / Primary Antibodies

Phospho-ERK 1/2 (Y222/205) Mouse Monoclonal Antibody (4G3)

SKU : BHA13715368

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM40286
Background	MAPK1 (mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for MAPK1
Clonality	Monoclonal
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Host	Mouse
Immunogen	Synthetic Peptide of Phospho-ERK 1/2 (Y222/205) at AA range of 140-220
Isotype	Mouse IgG1
Reactivity	Human, Mouse, Rat

Gene Id	5594/5595

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715368	ABM40286	30ul	$109		Add to Cart
BHA13715368	ABM40286	100ul	$239		Add to Cart
BHA13715368	ABM40286	200ul	$379		Add to Cart

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