The BM8.1 antibody is specific for mouse F4/80 antigen, a 125 kDa transmembrane protein widely expressed by members of the mononuclear phagocyte system and considered to be a key marker for mature macrophage cells. F4/80 is differentially expressed during myeloid cell development, and may be regulated by certain cytokines within the tissue microenvironment. Other cell types shown to express this antigen include Langerhans cells, Kupffer cells and dendritic cell subsets. BM8.1 is widely used together with antibodies to CD115 (c-fms), CD11b and CD11c to identify myeloid / macrophage cells by flow cytometry.
Formulation
Liquid, PerCP-Cyanine5.5 conjugated
Isotype
Rat IgG2b, kappa
Raised In
Rat
Shipping Condition
Ice packs
Species Reactivity
Mouse
Specificity
Mouse
Note
Flow cyt
Clone No
BM8.1
Purity
Affinity Purified
Storage Buffer
10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3,0.1% gelatin, pH7.2
Applications
Flow cyt
Reviews of PerCP-Cyanine5.5 Anti-Mouse F4/80 Antigen (BM8.1)