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Home / Primary Antibodies / Monoclonal Antibodies

PAX-8

SKU : BHA15100452

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Mfr.No.	ANB31-5M
Clonality	Monoclonal
Description	PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. PAX proteins play critically important roles in development by regulating transcriptional networks responsible for embryonic patterning and organogenesis; a subset of PAX proteins also maintain functional importance during postnatal development. It is expressed during organogenesis of thyroid gland, kidney and Mullerian system. Research studies have implicated genetic mutations that result in aberrant expression of PAX genes in a number of cancer subtypes (1-3), with members of subgroups II and III identified as potential mediators of tumor progression. PAX8 antibody is expressed in a high percentage of ovarian serous carcinomas, endometrioids, thyroid follicular carcinomas, renal clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX8 is a useful marker in distinguishing ovarian carcinoma from mammary carcinomas.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	PAX8/2774R
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
ANB31-5M	ANB31-5M	6 mL	$310		Add to Cart
ANB31-10M	ANB31-10M	100 tests - i6000	$582		Add to Cart
AYB31-50D	AYB31-50D	50 tests - Xmatrx	$327		Add to Cart
AYB31-YCD	AYB31-YCD	160 tests - Xmatrx	$795		Add to Cart
NUB31-UC	NUB31-UC	1ml Conc	$506		Add to Cart
NUB31-5UC	NUB31-5UC	0.5ml Conc	$353		Add to Cart

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