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Home / Primary Antibodies

P44/42 MAPK (ERK1/2) Monoclonal Antibody

SKU : BHA13715135

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0071
Alternative Names	MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p
Background	MAPK1 (mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for MAPK1.
Clonality	Monoclonal
Description	Mouse Anti-P44/42 MAPK (ERK1/2) Monoclonal Antibody
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host	Mouse
Immunogen	Synthetic Peptide
Immunogen Region	Synthetic Peptide
Isotype	Mouse IgG1
Molecular Weight	44, 42 KD
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human, Mouse, Rat
Tag	P44
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:50-1:100).

Accession Number	P27361/P28482
Gene Id	5594/5595, 5594/5595

Concentration	1 mg/ml, 1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IHC-P

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715135	ABM0071	100 uL	$229		Add to Cart

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