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Home / Antibodies

P-Glycoprotein (ABCB1) Antibody (F49437)

SKU : BHA17101445

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NSJ Bioreagents

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Mfr.No.	F49437, F49437-0.08ML, F49437-0.4ML
Clonality	Polyclonal
Description	The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 647-677 from the human protein was used as the immunogen for this P-Glycoprotein antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P08183

Format	Purified
Purification	Purified
Storage	Aliquot the P-Glycoprotein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Weste blot: 1:1000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17101445-1	F49437-0.08ML	0.08ml	$165		Add to Cart
BHA17101445-2	F49437-0.4ML	0.4ml	$379		Add to Cart

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