Mouse Anti-Rat Neuroligin-3 Monoclonal IgG1

Mfr.No.	SMC-471, SMC-471D, SMC-471D-A390, SMC-471D-A488, SMC-471D-A594, SMC-471D-APC, SMC-471D-BI, SMC-471D-FITC, SMC-471D-HRP, SMC-471D-PCP, SMC-471D-RPE, SMC-471S
Immunogen Species	Rat
Alternative Names	Gliotactin homolog Antibody, Neuroligin-3 Antibody, Nlgn3 Antibody, NLGN3_HUMAN Antibody
Categories	Antibodies
Cellular Localization	Cell Membrane, Cell Junction, Synapse
Certificate Of Analysis	1 ug/ml of SMC-471 was sufficient for detection of Neuroligin 3 in 20 ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Clonality	Monoclonal
Description	Mouse Anti-Rat Neuroligin 3 Monoclonal IgG1
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host	Mouse
Gross Weight (kg)	1.4
Immunogen	Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2., Rattus Norvegicus (Rat)
Immunogen Region	Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.
Isotype	IgG1
Launch Date	2013/10/29
Net Weight (g)	0.1
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Species	Rattus Norvegicus (Rat)
Species Reactivity Medium	Mouse, Rat, Human

Antigen	Neuroligin 3
Swissprot	Q62889
Accession Number	AAA97871
Gene Id	171297
Target	Neuroligin 3
Clone No	S110-29
Research Area	Cell Markers, Neuron Markers, Postsynaptic Markers, Neuroscience

Buffer	PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Concentration	1 mg/ml
Dilutions	WB (1:1000); optimal dilutions for assays should be determined by the user.
Purification	Protein G Purified
Scientific Background	Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.
Shipping Temperature	Blue Ice or 4°C
Specificity	Detects ~110kDa. Does not cross-react with Neuroligin-1, -2, -4 or -4.
Storage	-20ºC
Storage Buffer	PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
Storage Temperature	-20°C

Applications	IHC, WB, ICC/IF
Description	WB ; IHC ; ICC ; IF
Dilution	WB (1:1000); optimal dilutions for assays should be determined by the user.

Product Manual	SDS
SDS

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Combination SKU	Supplier No.	Conjugate	Size	Your price
BHA11904818-1	SMC-471D	Unconjugated	100 ug	$337	Add to Cart
BHA11904818-2	SMC-471D-A390	ATTO 390	100 ug	$392	Add to Cart
BHA11904818-3	SMC-471D-A488	ATTO 488	100 ug	$391	Add to Cart
BHA11904818-4	SMC-471D-A594	ATTO 594	100 ug	$391	Add to Cart
BHA11904818-5	SMC-471D-APC	APC	100 ug	$390	Add to Cart
BHA11904818-6	SMC-471D-BI	Biotin	100 ug	$386	Add to Cart
BHA11904818-7	SMC-471D-FITC	FITC	100 ug	$381	Add to Cart
BHA11904818-8	SMC-471D-HRP	HRP	100 ug	$377	Add to Cart
BHA11904818-9	SMC-471D-PCP	PerCP	100 ug	$390	Add to Cart
BHA11904818-10	SMC-471D-RPE	RPE	100 ug	$388	Add to Cart
BHA11904818-11	SMC-471S	Unconjugated	12 ug	$45	Add to Cart

Neuroligin-3 Antibody, Clone N110/29 (SMC-471)

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