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Home / Antibodies

NANOG Antibody (F44247)

SKU : BHA17100765

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Mfr.No.	F44247, F44247-0.08ML, F44247-0.4ML
Clonality	Polyclonal
Description	NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-(CG)(GA)(CG)C(GC)ATTAN(GC)-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation. (UniProt)
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 15-49 from the human protein was used as the immunogen for this NANOG antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	NANOG
Uniprot	Q9H9S0

Format	Purified
Purification	Purified
Storage	Aliquot the NANOG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IF, IHC, FACS, ELISA
Dilution	Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17100765-1	F44247-0.08ML	0.08ml	$165		Add to Cart
BHA17100765-2	F44247-0.4ML	0.4ml	$389		Add to Cart

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