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Home / Antibodies

MEK2 Monoclonal Antibody

SKU : BHA13715151

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0087
Background	The protein encoded by MAP2K2 (mitogen-activated protein kinase kinase 2) is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for MAP2K2
Clonality	Monoclonal
Formulation	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Host	Mouse
Immunogen	Synthesized peptide derived from human MEK-2 around the non-phosphorylation site of T394
Isotype	Mouse IgG1
Reactivity	Human, Mouse, Rat

Gene Id	5605

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715151	ABM0087	100ul	$229		Add to Cart

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