MEK-1/2 (phospho Ser218/222) Polyclonal Antibody-BHA13701161

Mfr.No.	ABP50356
Alternative Names	MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein k
Background	Mitogen-activated protein kinase 1 encoded by MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. Mitogen-activated protein kinase 1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway,Mitogen-activated protein kinase 1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	Polyclonal
Description	Rabbit Anti-MEK-1/2 (phospho Ser218/222) Polyclonal Antibody
Formulation	Liquid solution
Host	Rabbit
Immunogen	Synthesized peptide derived from human MEK-1/2 around the phosphorylation site of S218/222
Immunogen Region	Synthesized peptide derived from human MEK-1/2 around the phosphorylation site of S218/222
Isotype	Rabbit IgG
Others	Phospho-MEK-1/2 (S218/222) Polyclonal Antibody detects endogenous levels of MEK-1/2 protein only when phosphorylated at S218/222. Observed Band (KD): 48
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human, Mouse, Rat
Shipping	Gel pack with blue ice.
Tag	Dual specificity mitogen-activated protein kinase kinase 1
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Accession Number	Q02750/P36507
Gene Id	5604/5605

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	ELISA, IHC-P, WB
Dilution	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.