L1CAM Antibody (CSB-PA266419)

Mfr.No.	CSB-PA266419
Alternative Names	Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171)
Categories	Primary Antibodies
Host	Rabbit
Immunogen	Synthetic peptide from Human protein at AA range: 151-200
Involvement In Disease	Hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS); Mental retardation, aphasia, shuffling gait, and adducted thumbs syndrome (MASA); Agenesis of the corpus callosum, X-linked, partial (ACCPX)
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Species	Homo Sapiens (Human)
Subcellular Location	Cell membrane, Single-pass type I membrane protein, Cell projection, growth cone, Cell projection, axon, Cell projection, dendrite

Antigen	L1CAM
Uniprot	P32004
Database Links	HGNC:6470 OMIM:303350 KEGG:hsa:3897 STRING:9606.ENSP00000359074 UniGene:Hs.522818
Function	Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
Protein Families	Immunoglobulin superfamily, L1/neurofascin/NgCAM family

Buffer	PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form	Liquid
Format	Liquid
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.