Janus kinase 2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for JAK2 exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, Liquid solution
Host
Rabbit
Immunogen
Synthesized peptide derived from human JAK2 around the phosphorylation site of Y1007
Immunogen Region
Synthesized peptide derived from human JAK2 around the phosphorylation site of Y1007
Isotype
Rabbit IgG
Molecular Weight
130 KD
Others
Phospho-JAK2 (Y1007) Polyclonal Antibody detects endogenous levels of JAK2 protein only when phosphorylated at Y1007.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity
Human, Mouse, Rat
Tag
Tyrosine-protein kinase JAK2
Note
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
Accession Number
O60674
Gene Id
3717, 3717
Concentration
1 mg/ml, 1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer
PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.