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Home / Antibodies

IKB alpha Antibody (IKBa) (F48068)

SKU : BHA17101139

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Mfr.No.	F48068, F48068-0.08ML, F48068-0.4ML
Clonality	Polyclonal
Description	NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	A portion of amino acids 1-30 from the human protein was used as the immunogen for this IKBa antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P25963

Format	Purified
Purification	Purified
Storage	Aliquot the IKBa antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Weste blot: 1:1000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17101139-1	F48068-0.08ML	0.08ml	$165		Add to Cart
BHA17101139-2	F48068-0.4ML	0.4ml	$379		Add to Cart

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