JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

HMGCR antibody

SKU : BHA10810043

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Fine Test

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	FNab10055
Background	HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Immunogen Region	3-hydroXy-3-methylglutaryl-Coenzyme A reductase
Isotype	IgG
Molecular Weight	120 kDa
Reactivity	Human
Recommended Dilution	IHC: 1:20-1:200
Synonyms	HMG CoA reductase, HMGCR, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMDH

Uniprot	P04035
Gene Id	3156
Research Area	Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10055.pdf" target="_blank">Data Sheet</ a>

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10810043	FNab10055	100ug	$260		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.