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Home / Antibodies

HES1 Antibody (F53422)

SKU : BHA17102333

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NSJ Bioreagents

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Mfr.No.	F53422, F53422-0.08ML, F53422-0.4ML
Clonality	Polyclonal
Description	Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	This HES1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 203-236 amino acids from the C-terminal region of human HES1.
Isotype	Ig
Predicted Reactivity	Mouse
Reactivity	Mouse
Recombinant	No

Uniprot	Q14469

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the HES1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Dilution	Weste blot: 1:2000

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17102333-1	F53422-0.08ML	0.08ml	$165		Add to Cart
BHA17102333-2	F53422-0.4ML	0.4ml	$379		Add to Cart

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