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Home / Primary Antibodies / Monoclonal Antibodies

GluA1 Antibody, Clone N355/1 (SMC-440)

BHA11904267
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Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Antigen GluR1
Swissprot P19490
Accession Number NP_113796
Gene Id 50592
Target GluR1
Clone No S355-1
Research Area Neurotransmitter Receptors, AMPA Receptors, Cell Signaling, Glutamate Receptors, Neuroscience
Buffer PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Concentration 1 mg/ml
Dilutions WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification Protein G Purified
Scientific Background Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
Shipping Temperature Blue Ice or 4°C
Specificity Detects ~100kDa. Does not cross-react with GluR2.
Storage -20ºC
Storage Buffer PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
Storage Temperature -20°C
Applications IHC, WB, ICC/IF
Description WB ; IHC ; ICC ; IF
Dilution WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Product Manual SDS
SDS
Reference 1. Potier M.C., Spillantini M.G., Carter N.P. (1992) DNA Seq. 2(4): 211-218.

2. Puckett, C., et al. (1991) Proc. Nat. Acad. Sci. USA 88(17): 7557-7561.

3. Gregor, P., et al. (1993) Proc. Nat. Acad. Sci. USA 90: 3053-3057.
Combination SKU Supplier No. Conjugate Size Your price Quantity
BHA11904267-1 SMC-440D Unconjugated 100 ug $337
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BHA11904267-2 SMC-440D-A390 ATTO 390 100 ug $392
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BHA11904267-3 SMC-440D-A488 ATTO 488 100 ug $391
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BHA11904267-4 SMC-440D-A594 ATTO 594 100 ug $391
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BHA11904267-5 SMC-440D-APC APC 100 ug $390
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BHA11904267-6 SMC-440D-BI Biotin 100 ug $386
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BHA11904267-7 SMC-440D-FITC FITC 100 ug $381
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BHA11904267-8 SMC-440D-HRP HRP 100 ug $377
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BHA11904267-9 SMC-440D-PCP PerCP 100 ug $390
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BHA11904267-10 SMC-440D-RPE RPE 100 ug $388
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BHA11904267-11 SMC-440S Unconjugated 12 ug $45
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