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Home / Primary Antibodies / Monoclonal Antibodies

GITR

SKU : BHA15100337

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BioGenex Laboratories

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Mfr.No.	AW915-50D
Clonality	Monoclonal
Description	GITR (Glucocorticoid-induced TNF receptor family-regulated gene), also known as TNFRS18, belongs to the TNF receptor superfamily (TNFRS). GITR is widely expressed in different cells of the immune system and its activation triggers the production of proinflammatory cytokines. GITR is constitutively expressed at high levels on Tregs and at low levels on na?ve and memory T cells. Activation of GITR with its ligand (GITRL) or with anti-GITR agonist antibodies (such as DTA-1) provides strong costimulatory signals for T cells. Furthermore, activation of GITR with agonistic antibodies has been shown to amplify the antitumor immune responses in animal models by increasing the proliferation and function of effector T cells and possibly also by abrogating the suppressive function of Tregs cells.
Isotype	IgG
Reactivity	Human

Clone No	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AW915-50D	AW915-50D	6 mL	$467		Add to Cart
AW915-YCD	AW915-YCD	0.5ml Conc	$1135		Add to Cart

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