This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality
polyclonal
Host
Rabbit
Immunogen
galactosylceramidase
Immunogen Region
galactosylceramidase
Isotype
IgG
Molecular Weight
80 kDa, 50 kDa, 30 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Synonyms
Gacy, galactosylceramidase, Galc, twi, twitcher
Uniprot
P54803
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10708.pdf" target="_blank">Data Sheet</ a>