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Home / Primary Antibodies / Polyclonal Antibodies

FGFR1OP Antibody (CSB-PA002560)

SKU : BHA10536844

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA002560
Alternative Names	FGFR1OP; FOP; FGFR1 oncogene partner
Categories	Primary Antibodies
Host	Rabbit
Immunogen	Synthesized peptide derived from the C-terminal region of Human FOP.
Involvement In Disease	A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity (PubMed:9949182).
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Species	Homo Sapiens (Human)
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole, Cytoplasm, cytoskeleton, cilium basal body

Antigen	FGFR1OP
Uniprot	O95684
Database Links	HGNC:17012 OMIM:605392 KEGG:hsa:11116 STRING:9606.ENSP00000355812 UniGene:Hs.487175
Function	Required for anchoring microtubules to the centrosomes
Protein Families	FGFR1OP family
Tissue Specificity	Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.

Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form	Liquid
Format	Liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications

WB, IHC, IF, ELISA

Description

WB ; IHC ; IF ; ELISA, WB ; ELISA ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC	1:100-1:300
IF	1:200-1:1000
ELISA	1:10000

Tested Application

WB,IHC,IF,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/10000

Datasheet
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10536844	CSB-PA002560	50ug	$119		Add to Cart
BHA10536844	CSB-PA002560	100ug	$199		Add to Cart

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