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Home / Primary Antibodies / Polyclonal Antibodies

EZH2 Antibody

SKU : BHA17102395

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NSJ Bioreagents

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Mfr.No.	F53753, F53753-0.08ML, F53753-0.4ML
Clonality	Polyclonal
Description	EZH2, SUZ12, and EED form a complex that methylates nucleosomal histone H3 at Lys27. EZH2 contains a SET domain, a signature motif for all known histone lysine methyltransferases except the H3-K79 methyltransferase DOT1, and is therefore likely to be the catalytic subunit. Consequently, EZH2 is thought to regulate gene expression by controlling chromatin structure. Several lines of evidence suggested a critical role for the EZH2 protein during normal and perturbed development of the hematopoietic and central nervous systems. The EZH2 protein has been shown to associate with the VAV1 protooncoprotein and with the XNP protein, the product of a gene associated with mental retardation. Additionally, due to mapping of EZH2 to the 7q35-q36 chromosomal region associated with myeloid disorders, this protein is suggested to participate in the genetic events triggering myeloid leukemia.
Formulation	In 1X PBS, pH 7.4, with 0.09% sodium azide
Host	Rabbit
Immunogen Region	This EZH2 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human EZH2.
Isotype	Ig
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	EZH2
Uniprot	Q15910

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	Aliquot the EZH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA
Dilution	Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102395	F53753, F53753-0.08ML, F53753-0.4ML	0.08ml	$199		Add to Cart
BHA17102395	F53753, F53753-0.08ML, F53753-0.4ML	0.4ml	$199		Add to Cart

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