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Home / Antibodies

ERCC1 Monoclonal Antibody

SKU : BHA13715093

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0029
Background	The product of ERCC1 functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. ERCC excision repair 1, endonuclease non-catalytic subunit forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in ERCC1 result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of ERCC1 may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for ERCC1. The last exon of ERCC1 overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand
Clonality	Monoclonal
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Host	Mouse
Immunogen	Synthetic Peptide
Isotype	Mouse IgG1
Reactivity	Human

Gene Id	2067

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715093	ABM0029	100ul	$229		Add to Cart

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