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Home / Primary Antibodies / Polyclonal Antibodies

CYCS Antibody (CSB-PA006328EA01HU)

SKU : BHA10501466

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA006328EA01HU
Alternative Names	CYCS,CYC
Categories	Primary Antibodies
Clonality	polyclonal
Description	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Host	Rabbit
Immunogen	Recombinant Human Cytochrome c protein (2-105AA)
Involvement In Disease	Thrombocytopenia 4 (THC4)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Species	Homo Sapiens (Human)
Subcellular Location	Mitochondrion intermembrane space

Antigen	CYCS
Uniprot	P99999
Database Links	HGNC:19986 OMIM:123970 KEGG:hsa:54205 STRING:9606.ENSP00000307786 UniGene:Hs.437060
Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; FUNCTION
Pathway	p53 signaling pathway Apoptosis
Protein Families	Cytochrome c family
Research Area	Apoptosis

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Format	Liquid
Purification	Caprylic Acid Ammonium Sulfate Precipitation purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	0.1mol/L NaCl, 15mmol/L NaN3, PH7.2

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC, IHC ; ELISA

Dilution

WB	1:500-5000
IHC	1:200-1:500

Tested Application

ELISA,IHC;Recommended dilution:IHC:1:20-1:200

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10501466	CSB-PA006328EA01HU	50ug	$166		Add to Cart
BHA10501466	CSB-PA006328EA01HU	100ug	$299		Add to Cart

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