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Home / Primary Antibodies / Polyclonal Antibodies

Cleaved-F12 (I20) Antibody (CSB-PA008169)

SKU : BHA10539682

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA008169
Alternative Names	F12; Coagulation factor XII; Hageman factor; HAF
Categories	Primary Antibodies
Host	Rabbit
Immunogen	Synthesized peptide derived from the N-terminal region of Human Factor XII HC.
Involvement In Disease	Factor XII deficiency (FA12D); Hereditary angioedema 3 (HAE3)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Species	Homo Sapiens (Human)
Subcellular Location	Secreted

Antigen	F12
Uniprot	P00748
Database Links	HGNC:3530 OMIM:234000 KEGG:hsa:2161 STRING:9606.ENSP00000253496 UniGene:Hs.1321
Function	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
Pathway	Complement and coagulation cascades
Protein Families	Peptidase S1 family

Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form	Liquid
Format	Liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications

WB, IHC, ELISA

Description

WB ; IHC ; ELISA, WB ; ELISA ; IHC

Dilution

WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:20000

Tested Application

WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Datasheet
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10539682	CSB-PA008169	50ug	$119		Add to Cart
BHA10539682	CSB-PA008169	100ug	$199		Add to Cart

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