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Home / Primary Antibodies / Monoclonal Antibodies

CDK1

SKU : BHA15100331

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Mfr.No.	AM905-5M
Clonality	Monoclonal
Description	CDK1 (Cyclin-dependent kinase 1), also known as CDC2 (cell division cycle protein 2 homolog) is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation and the only CDK that can initiate the onset of mitosis. At the onset of mitosis activation of CDK1 occurs rapidly. Subsequently, CDK1 forms complexes with its cyclin partners (Cyclin A2 and Cyclin B1) and phosphorylates a variety of target substrates (over 75 have been identified in budding yeast), leading to nuclear envelope breakdown, chromosome condensation, mitotic spindle assembly and cell cycle progression. Derangement of p53 signaling or of DNA damage checkpoints indirectly leads to the deregulation of CDK1, and high cyclin B1 expression is generally associated with a more aggressive cancer phenotype. Diseases associated with CDK1 include Breast Cancer and Hepatocellular Carcinoma.
Host	Mouse
Isotype	IgG
Reactivity	Human
Species	Mouse

Antigen	CDK1
Clone No	A17.1.1
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM905-5M	AM905-5M	6 mL	$339		Add to Cart
AM905-10M	AM905-10M	100 tests - i6000	$637		Add to Cart
AX905-50D	AX905-50D	50 tests - Xmatrx	$356		Add to Cart
AX905-YCD	AX905-YCD	160 tests - Xmatrx	$871		Add to Cart
MU905-UC	MU905-UC	1ml Conc	$696		Add to Cart
MU905-5UC	MU905-5UC	0.5ml Conc	$489		Add to Cart

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