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Home / Primary Antibodies

Caveolin-1 Polyclonal Antibody

SKU : BHA13715199

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABP0067
Background	The scaffolding protein (caveolin 1) encoded by CAV1 is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in CAV1 have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1
Clonality	Polyclonal
Formulation	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Host	Rabbit
Immunogen	Synthesized peptide derived from the C-terminal region of human Caveolin-1 at AA range: 100-180
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat

Gene Id	857

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715199	ABP0067	100ul	$229		Add to Cart

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