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Home / Primary Antibodies / Monoclonal Antibodies

Biotinylated Anti-SIRP?(DM8) antibody, Rabbit mAb

SKU : BHA18100122

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DIMA Biotechnology

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Mfr.No.	DME100008B
Background	The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negatIVe regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proXimity to each other on chromosome 20p13. Multiple alternatIVely spliced transcript variants have been determined for this gene. (proVIded by RefSeq, Jul 2008)
Clonality	Monoclonal
Host	Rabbit
Isotype	Rabbit IgG
Reactivity	Human
Solubility	Flow Cyt 1/100; IP 1/30
Synonyms	BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	Flow Cyt, ELISA

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SKU	Supplier No.	Size	Your price	Quantity
BHA18100122	DME100008B	100 ug	$597		Add to Cart
BHA18100122	DME100008B	10 ug	$90		Add to Cart

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