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Home / Primary Antibodies / Polyclonal Antibodies

Autotaxin antibody

SKU : BHA10810385

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Mfr.No.	FNab10430
Background	Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Clonality	polyclonal
Host	Rabbit
Immunogen	ectonucleotide pyrophosphatase/phosphodiesterase 2
Immunogen Region	ectonucleotide pyrophosphatase/phosphodiesterase 2
Isotype	IgG
Molecular Weight	50kd, 60kd, 110-120kd
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500-1:1000; IHC: 1:20-1:200
Synonyms	ATX, ATX X, Autotaxin, E NPP 2, ENPP2, FLJ26803, LysoPLD, PD IALPHA, PDNP2

Uniprot	Q13822
Gene Id	5168
Research Area	Immunology, Cardiovascular, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:1000; IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10430.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810385	FNab10430	100ug	$240		Add to Cart

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