Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).
Host
Rabbit
Immunogen
atonal homolog 1
Isotype
IgG
Molecular Weight
38kd
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
ATH1, BHLHA14
Antigen
Atoh1
Uniprot
Q92858
Gene Id
474
Research Area
Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)