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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ZIP7/SLC39A7 Antibody Picoband®

SKU : BHA21004862

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Mfr.No.	A07719-4, A07719-4-10ug, A07719-4-Biotin, A07719-4-Cy3, A07719-4-Dylight488, A07719-4-Dylight550, A07719-4-Dylight594, A07719-4-FITC, A07719-4-HRP, A07719-4-APC, A07719-4-PE, A07719-4-iFluor647, A07719-4-carrier-free
Alternative Names	hook microtubule tethering protein 3
Background	Zinc transporter SLC39A7 (ZIP7), also known as solute carrier family 39 member 7, is a protein that in humans is encoded by the SLC39A7 gene. The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ZIP7/SLC39A7 Antibody Picoband® catalog # A07719-4. Tested in ELISA, ICC/IF, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesic
Host	Rabbit
Immunogen Region	E.coli-derived human ZIP7/SLC39A7 recombinant protein (Position: F154-Q384).
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Protein Hook homolog 3; h-hook3; Hhk3; HOOK3
Tissue Specificity	Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q92504
Gene Id	7922
Gene Name	SLC39A7
Subcellular Location	Cytoskeleton. Golgi apparatus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Ando, A., Kikuti, Y. Y., Shigenari, A., Kawata, H., Okamoto, N., Shiina, T., Chen, L., Ikemura, T., Abe, K., Kimura, M., Inoko, H. cDNA cloning of the human homologues of the mouse Ke4 and Ke6 genes at the centromeric end of the human MHC region. Genomics 35: 600-602, 1996. 2. Anzilotti, C., Swan, D. J., Boisson, B., Deobagkar-Lele, M., Oliveira, C., Chabosseau, P., Engelhardt, K. R., Xu, X., Chen, R., Alvarez, L., Berlinguer-Palmini, R., Bull, K. R., and 33 others. An essential role for the Zn(2+) transporter ZIP7 in B cell development. Nature Immun. 20: 350-361, 2019. 3. Aziz, N., Maxwell, M. M., Brenner, B. M. Coordinate regulation of 11-beta-HSD and Ke6 gene in cpk mouse: implications for steroid metabolic defect in PKD. Am. J. Physiol. 267: F791-F797, 1994.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004862-1	A07719-4	-	100 ug	$370		Add to Cart
BHA21004862-2	A07719-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21004862-3	A07719-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004862-4	A07719-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004862-5	A07719-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004862-6	A07719-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004862-7	A07719-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004862-8	A07719-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21004862-9	A07719-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21004862-10	A07719-4-APC	APC	100 ug	$670		Add to Cart
BHA21004862-11	A07719-4-PE	PE	100 ug	$670		Add to Cart
BHA21004862-12	A07719-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004862-13	A07719-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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