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Home / Primary Antibodies

Anti-WWOX Antibody

BHA10917426
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Buffer PBS, pH 7.4 with 0.02% Sodium Azide
Concentration 100µg/100ul
Description Specificity: Not yet tested in other species.
Relevance: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB, ELISA
Description For research use only
Peptide ELISA titer: 1:80,000
Western blot analysis: 1:500-1000
Optimal dilutions/concentrations should be determined by the end use., WB ; ELISA
Dilution

ELISA1:80,000
WB1:500-1000
SKU Supplier No. Size Your price Quantity
BHA10917426 y058200 100 ul $217.50
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