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Home / Primary Antibodies / Polyclonal Antibodies

Anti-VE-Cadherin CDH5-Antibody Picoband®

SKU : BHA21007287

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Mfr.No.	PA2079, PA2079-10ug, PA2079-Biotin, PA2079-Cy3, PA2079-Dylight488, PA2079-Dylight550, PA2079-Dylight594, PA2079-FITC, PA2079-HRP, PA2079-APC, PA2079-PE, PA2079-iFluor647, PA2079-carrier-free
Alternative Names	Cadherin-5
Background	CDH5 (Cadherin 5), also known as VE-cadherin, is a type of cadherin. It is encoded by the human gene CDH5. Kremmidiotis et al. (1998) mapped the human CDH5 gene to 16q22.1 using somatic cell hybrid panels. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Therefore it was concluded that VE-cadherin serves the purpose of maintaining newly formed vessels.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-VE-Cadherin CDH5-Antibody catalog # PA2079. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important r
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human VE Cadherin, different from the related mouse and rat sequences by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Cadherin-5;7B4 antigen;Vascular endothelial cadherin;VE-cadherin;CD144;CDH5;
Tissue Specificity	Endothelial tissues and brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P33151
Gene Name	CDH5
Sequence	Belongs to the annexin family.
Subcellular Location	Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat, By Heat<br>

Reference	1. Huber, P., Dalmon, J., Engiles, J., Breviario, F., Gory, S., Siracusa, L. D., Buchberg, A. M., Dejana, E. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (Cdh5). Genomics 32: 21-28, 1996.<br /><br />2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007287-1	PA2079	-	100 ug	$370		Add to Cart
BHA21007287-2	PA2079-10ug	Sample	10 ug	$99		Add to Cart
BHA21007287-3	PA2079-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007287-4	PA2079-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007287-5	PA2079-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007287-6	PA2079-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007287-7	PA2079-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007287-8	PA2079-FITC	FITC	100 ug	$570		Add to Cart
BHA21007287-9	PA2079-HRP	HRP	100 ug	$570		Add to Cart
BHA21007287-10	PA2079-APC	APC	100 ug	$670		Add to Cart
BHA21007287-11	PA2079-PE	PE	100 ug	$670		Add to Cart
BHA21007287-12	PA2079-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007287-13	PA2079-carrier-free	carrier-free	100 ug	$370		Add to Cart

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