JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Home / Antibodies

Anti-VE Cadherin Antibody

BHA10917653
Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
Request More Infos
Order Now

Credit card payments now incur a 3% fee.

Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
Ask Merchant
Request More Infos
Sample Request
Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 100µg/100ul
Description Specificity: This Polyclonal antibody is directed against human VE Cadherin protein. The product was purified from serum by protein A chromatography. Expect reactivity with human VE Cadherin. Cross-reactivity with VE Cadherin from other sources has not been determined.
Relevance: VE-cadherin (vascular endothelium cadherin), also known as Cadherin-5, is an endothelial cell-specific adhesion molecule localized at intracellular junctions (1,2). The protein belongs to the cadherin superfamily of adhesion molecules(3). VE-cadherin plays a pivotal role in vascular structure assembly. Endothelial cells fail to organize in a vessel-like pattern if the VE-cadherin gene is disrupted(4). In this aspect, VE-cadherin is a critical component of a protein complex which controls endothelial cell tube formation(5). VE-cadherin is also critical for maintenance of the endothelium. Following disruption of endothelial cell monolayers with an anti-VE-cadherin antibody, endothelial cells rapidly resynthesize VE-cadherin in order to restore their intracellular junctions(6). Human VE-cadherin has a molecular mass of approximately 87,500 based on the deduced amino acid sequence and is 83% and 79% homologous to porcine and murine VE-cadherin at the amino acid level.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/500~5000.
Predicted molecular weight: 88 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:500~5000
SKU Supplier No. Size Your price Quantity
BHA10917653 Y080032 100 ul $187.50
Add to Cart