JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-VAMP-2 Antibody

SKU : BHA21300673

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	ANR-007, ANR-007-CF_0.2 ml, ANR-007_0.2 ml, ANR-007_25 mcl, ANR-007_50 mcl
Lead Time	1-2 Business Days
Immunogen Species	Rat
Background	VAMP-2 (also known as synaptobrevin-2) is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionary conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2.SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.VAMP-2, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located on the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.VAMP-2 has been extensively studied for its role on neuronal and neuroendocrine cell exocytosis where it functions as the vesicle membrane protein v-SNARE, which together with the plama membrane t-SNARE protein Syntaxin 1 and the membrane-associated SNAP-25 (synaptosome-associated protein 25 kDa), forms a trimeric, four-helical complex, which drives fusion of the two opposing bilayers1,2.VAMP-2 is the target of the tetanus neurotoxin (TeNT) and of several botulinum neurotoxin (BoNT) types: type B, D, F, and G. The neurotoxins cause specific proteolytic degradation of the VAMP-2 protein, which in turn causes SNARE complex disruption and inhibition of neurotransmitter release3.
Clonality	Polyclonal
Description	Alomone Labs is pleased to offer a highly specific antibody directed against the intracellular N-terminal domain of rat VAMP-2. Anti-VAMP-2 Antibody (#ANR-007) can be used in western blot and immunohistochemical applications, and has been designed to recognize VAMP-2 from rat, mouse and human samples.
Formulation	PBS pH7.4
Host	Rabbit
Immunogen Region	Cytoplasmic, N-terminus
Isotype	Rabbit IgG
Reactivity	Rat, Mouse
Reconstitution	0.2 ml double distilled water (DDW).
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Synonyms	Vesicle-associated membrane protein 2, Synaptobrevin 2, Syb2
UNSPSC Code	41116161
Note	Homology: Human, bovine, Macaca mulata - 25/26 amino acid residues identical Peptide confirmation: Confirmed by DNA sequence and SDS-PAGE Negative Control: BLP-NR007 Specifictiy: VAMP2 Is Toxin: No Standard quality control of each lot: Western blot analysis Antigen preadsorption control: 3 ug fusion protein per 1 ug antibody

Accession Number	P63045
Gene Id	24803
Target	Vesicle-associated membrane protein 2, Synaptobrevin 2, Syb2
Sequence	GST fusion protein with the sequence SATAATVPPAAPAGEGGPPAPPPNLT, corresponding to amino acid residues 2-27 of rat VAMP2

Conjugates	Unconjugated

Concentration	1 mg/ml
Form	Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.
Preservative	No Preservative
Purity	The serum was depleted of anti-GST antibodies by affinity chromatography on immobilized GST and then the IgG fraction was purified on immobilized antigen.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Storage Before Reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Applications	IF, IHC, WB
Dilution	Contact Alomone for information

Product Manual	SDS

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHA21300673-1	ANR-007-CF_0.2 ml	0.2 ml(Carrier Free)	$994		Add to Cart
BHA21300673-2	ANR-007_0.2 ml	0.2 ml	$795		Add to Cart
BHA21300673-3	ANR-007_25 mcl	25 mcl	$597		Add to Cart
BHA21300673-4	ANR-007_50 mcl	50 mcl	$697		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.