Anti-undefined Antibody RB1,2313R Unconjugated BHA10208284

Mfr.No.	5925-RBM3-P1ABX
Alternative Names	OSRC ; Osteosarcoma ; p105-Rb ; PP105 ; pp110 ; pRb ; Prepro retinoblastoma associated protein ; RB1 ; Retinoblastoma 1 ; Retinoblastoma-associated protein
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	13q14.2
Clonality	monoclonal
Description	Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Host	Rabbit
Immunogen	Recombinant full-length human Rb1 protein
Isotype	IgG
Positive Control	HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P06400
Gene Id	5925
Clone No	RB1, 2313R
Symbol	RB1
Weight	105kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., IHC-F

Dilution

Immunohistology (Formalin-fixed)

1-2μg/ml for 30 minutes at RT

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208284	5925-RBM3-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody RB1,2313R Unconjugated BHA10208284

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