Anti-undefined Antibody MMP3,1994R Unconjugated BHA10208248

Mfr.No.	4314-RBM3-P1ABX
Alternative Names	CHDS6 ; Matrix metalloproteinase 3 ; Matrix metalloproteinase-3 ; MGC126102 ; MGC126103 ; MGC126104 ; MMP 3 ; MMP-3 ; MMP3 ; Proteoglycanase ; SL-1 ; SL1 ; STMY ; STMY1 ; STR1 ; Stromelysin 1 ; Stromelysin-1 ; Transin 1
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, extracellular
Chromosome Location	11q22.2
Clonality	Monoclonal
Description	The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Host	Rabbit
Immunogen	Recombinant fragment of human MMP3 protein (around aa 317-327) (exact sequence is proprietary)
Isotype	IgG
Positive Control	Human prostate or lung tissue. A-431 cells.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P08254
Gene Id	4314
Clone No	MMP3, 1994R
Symbol	MMP3
Weight	57kDa

Buffer	200μg/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	0.5-1μg/ml
Immunohistology (Formalin-fixed)	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208248	4314-RBM3-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody MMP3,1994R Unconjugated BHA10208248

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