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Home / Primary Antibodies

Anti-UBE3A Antibody

SKU : BHA10901859

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y158085
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	Rabbit polyclonal UBE3A (1) antibody was raised against a recombinate human UBE3A protein 342-585aa (BC009271).
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: Human and predicted against mouse and rat.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	WB, IHC, ELISA
Description	WB ; IHC ; ELISA

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SKU	Supplier No.	Size	Your price	Quantity
BHA10901859	Y158085	100 ul	$217.50		Add to Cart

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