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Home / Antibodies

Anti-TNFRSF1A Antibody

SKU : BHA10918062

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058180
Categories	Primary Antibodies
Cellular Localization	Cell membrane,Type I membrane protein and Secreted
Clonality	polyclonal
Description	The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Host	Rabbit
Immunogen	a 14 amino acid peptide from near the N terminal residues of human TNFRSF1A protein
Isotype	IgG
Quantity	100 µl
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: Not yet tested in other species
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, ELISA

Description

For research use only
Peptide ELISA titer: 1:40,000-1:80,000
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end use be, WB ; ELISA

Dilution

ELISA	1:40,000-1:80,000
WB	1:200-500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10918062	Y058180	100 ul	$217.50		Add to Cart

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