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Home / Primary Antibodies

Anti-TGFB2 Antibody

SKU : BHA10900923

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058302
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	polyclonal
Description	This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]
Host	Rabbit
Immunogen	Rabbit polyclonal TGFB2 antibody was raised against a peptide from N terminal residues of human TGFB2 protein.
Isotype	IgG
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:1,000-1:10,000
Immunohistochemistry: 1:100-500
Optimal dilutions/concentrations should be determined by the end use., IHC ; ELISA

Dilution

ELISA	1:1,000-1:10,000
IHC	1:100-500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10900923	Y058302	100 ul	$217.50		Add to Cart

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