Anti-TGF beta1 Antibody

Mfr.No.	Y058105
Categories	Primary Antibodies
Clonality	polyclonal
Description	TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[
Host	Rabbit
Immunogen	partial recombinate protein
Quantity	100 µl
Reactivity	Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: TGF beta1 antibody detects endogenous levels of TGF1 beta1 protein. Not tested with other proteins Relevance: TGF beta 1 (Transforming Growth Factor Beta 1) is a multifunctional peptide capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed as well as non neoplastic tissues, release transforming growth factors; and essentially all cells possess a specific TGF beta 1 receptor. The multimodal nature of TGF beta 1 is seen in its ability to stimulate or inhibit cellular proliferation. TGF beta 1 plays a fundamental role in tissue growth and differentiation involvement in adipogenesis, myogenesis, chondrogenesis, osteogenesis, epithelial cell differentiation and immune cell function.
Format	Liquid
Purity	Protein A purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, IHC, ELISA

Description

Recommended dilutions Peptide ELISA: 1:80,000 WB: 1/200 - 1/1000
IHc:1/50-1/200
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user, WB ; IHC ; ELISA

Dilution

ELISA	1:80,000
WB	1:200-1:1000
IHC	1:50-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10916142	Y058105	100 ul	$217.50		Add to Cart

Anti-TGF beta1 Antibody

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