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Home / Primary Antibodies / Monoclonal Antibodies

Anti-TCP1 alpha Antibody Picoband® (monoclonal, 2E7)

SKU : BHA21001747

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Mfr.No.	M02389, M02389-10ug, M02389-Biotin, M02389-Cy3, M02389-Dylight488, M02389-Dylight550, M02389-Dylight594, M02389-FITC, M02389-HRP, M02389-APC, M02389-PE, M02389-iFluor647, M02389-carrier-free
Alternative Names	t-complex 1
Background	T-complex protein 1 subunit alpha is a protein that in humans is encoded by the TCP1 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alteate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TCP1 alpha Antibody Picoband® (monoclonal, 2E7) catalog # M02389. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vi
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human TCP1 alpha, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
Isotype	Mouse IgG1
Molecular Weight	60 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	T-complex protein 1 subunit alpha; TCP-1-alpha; CCT-alpha; TCP1; CCT1; CCTA
Tissue Specificity	Widely expressed. Highest level in placenta, liver, muscle and kidney.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P17987
Gene Id	6950
Gene Name	TCP1
Clone No	Clone: 2E7
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells

Reference	1. "Entrez Gene: TCP1 t-complex 1".<br /><br />2. Fonatsch C, Gradl G, Ragoussis J, Ziegler A (Oct 1987). "Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization". Cytogenet Cell Genet 45 (2): 10912.<br /><br />3. Willison K, Kelly A, Dudley K, Goodfellow P, Spurr N, Groves V, Gorman P, Sheer D, Trowsdale J (Nov 1987)."The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region". EMBO J 6 (7): 196774.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001747-1	M02389	100 ug	-	$370		Add to Cart
BHA21001747-2	M02389-10ug	10 ug	Sample	$99		Add to Cart
BHA21001747-3	M02389-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001747-4	M02389-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001747-5	M02389-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001747-6	M02389-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001747-7	M02389-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001747-8	M02389-FITC	100 ug	FITC	$570		Add to Cart
BHA21001747-9	M02389-HRP	100 ug	HRP	$570		Add to Cart
BHA21001747-10	M02389-APC	100 ug	APC	$670		Add to Cart
BHA21001747-11	M02389-PE	100 ug	PE	$670		Add to Cart
BHA21001747-12	M02389-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001747-13	M02389-carrier-free	100 ug	carrier-free	$370		Add to Cart

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