The simian virus 40 large T antigen plays important role in SV40 transfection and transformation of the cells. It binds to Rb and p53 suppressor proteins leading to the inactivation of suppressor pathway.
Host
Mouse
Immunogen
SV40 transformed mouse line B4; C-terminal
Isotype
IgG2a1
Quantity
100 µg
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Concentration
100µg/100ul
Description
Specificity: The antibody reacts with native and denatured large T antigen. It does not react with small T antigen of SV40 or large T antigen of BKV and human papovavirus.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB
Description
The optimal dilution for a specific application shouldbe determined by the investigator., WB